αβ TCR(+) T Cells, but Not B Cells, Promote Autoimmune Keratitis in B10 Mice Lacking γδ T Cells

PURPOSE. To investigate additional factors in the spontaneous development of keratitis previously reported in B10.TCRδ(−/−) female mice. METHODS. The study tested whether susceptible B10.TCRδ(−/−) mice have dry eyes compared with resistant B6.TCRδ(−/−) females and also rederived the B10.TCRδ(−/−) st...

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Detalhes bibliográficos
Main Authors: O'Brien, Rebecca L., Chain, Jennifer L., Aydintug, M. Kemal, Bohrer-Kunter, Dawn, Huang, Yafei, Hardy, Ian R., Cambier, John C., Lahmers, Kevin, Nuhsbaum, Tanja, Davidson, Richard, Sun, Deming, Born, Willi K.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292366/
https://ncbi.nlm.nih.gov/pubmed/22199243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8855
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