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Itch(−/−)αβ and γδ T cells independently contribute to autoimmunity in Itchy mice
E3 ubiquitin ligases determine which intracellular proteins are targets of the ubiquitin conjugation pathway and thus play a key role in determining the half-life, subcellular localization and/or activation status of their target proteins. Itchy mice lack the E3 ligase, Itch, and show dysregulation...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Hematology
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2359485/ https://ncbi.nlm.nih.gov/pubmed/18256323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-10-115667 |
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