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Contribution of αβ and γδ T cells to the generation of primary immunoglobulin G-driven autoimmune response in immunoglobulin-µ-deficient/lpr mice
Class switch recombination (CSR) is a T-cell-dependent mechanism regulating isotype switching in activated mature B cells. Recently we showed that T-cell-independent CSRs occur spontaneously during B lymphopoiesis, but such cells are negatively selected by Fas signalling. In immunoglobulin µ-deficie...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1782487/ https://ncbi.nlm.nih.gov/pubmed/15147570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.01883.x |
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