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Restricted cytokine production from mouse peritoneal macrophages in culture in spite of extensive uptake of plasmid DNA
The production of inflammatory cytokines from macrophages (Mφ), upon stimulation with plasmid DNA (pDNA) containing CpG motifs, is a critical process for DNA-based therapies such as DNA vaccination and gene therapy. We compared Mφ activation, following stimulation with naked pDNA, based on the produ...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1782422/ https://ncbi.nlm.nih.gov/pubmed/15009428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.01814.x |
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