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DNA and its cationic lipid complexes induce CpG motif-dependent activation of murine dendritic cells

Unmethylated CpG motifs in bacterial DNA, but not in vertebrate DNA, are known to trigger an inflammatory response of antigen-presenting cells (APC). In this study, we investigated the cytokine release from murine dendritic cells (DC) by the addition of various types of DNA in the free or complexed...

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Detalhes bibliográficos
Main Authors: Yoshinaga, Takaharu, Yasuda, Kei, Ogawa, Yoshiyuki, Nishikawa, Makiya, Takakura, Yoshinobu
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265891/
https://ncbi.nlm.nih.gov/pubmed/17199803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02451.x
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