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Enhanced immunostimulatory activity of oligodeoxynucleotides by Y-shape formation

DNA containing unmethylated CpG dinucleotides (CpG DNA) is a potent activator of innate and acquired immune responses. Although the sequence-specific immunostimulatory activity of CpG DNA has been extensively explored, little information is available about the importance of the stereochemical proper...

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Autori principali: Nishikawa, Makiya, Matono, Mitsuhiro, Rattanakiat, Sakulrat, Matsuoka, Nao, Takakura, Yoshinobu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566629/
https://ncbi.nlm.nih.gov/pubmed/18217956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02762.x
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