An essential function of the extreme C-terminus of MDM2 can be provided by MDMX

Lignende værker

• Mutational analysis of Mdm2 C-terminal tail suggests an evolutionarily conserved role of its length in Mdm2 activity toward p53 and indicates structural differences between Mdm2 homodimers and Mdm2/MdmX heterodimers
  af: Dolezelova, Pavlina, et al.
  Udgivet: (2012)
• Benzimidazoles Downregulate Mdm2 and MdmX and Activate p53 in MdmX Overexpressing Tumor Cells
  af: Mrkvová, Zuzana, et al.
  Udgivet: (2019)
• A Single Conserved Amino Acid Residue as a Critical Context-Specific Determinant of the Differential Ability of Mdm2 and MdmX RING Domains to Dimerize
  af: Pavlína Kosztyu, et al.
  Udgivet: (2019-04-01)
• Regulation of Mdm2-Directed Degradation by the C Terminus of p53
  af: Kubbutat, Michael H. G., et al.
  Udgivet: (1998)
• A Single Conserved Amino Acid Residue as a Critical Context-Specific Determinant of the Differential Ability of Mdm2 and MdmX RING Domains to Dimerize
  af: Kosztyu, Pavlína, et al.
  Udgivet: (2019)