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T-bet is essential for the progression of experimental autoimmune encephalomyelitis
Experimental autoimmune encephalomyelitis (EAE) is mediated by myelin-specific CD4(+) T helper 1 (Th1) cells, while recovery from the disease is associated with the presence of Th2 cells. Here we used animals with targeted deletion of the T-bet gene to determine its role in the progression of EAE. T...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Blackwell Science Inc
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1782298/ https://ncbi.nlm.nih.gov/pubmed/16827899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02385.x |
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