T-bet is essential for the progression of experimental autoimmune encephalomyelitis

Experimental autoimmune encephalomyelitis (EAE) is mediated by myelin-specific CD4(+) T helper 1 (Th1) cells, while recovery from the disease is associated with the presence of Th2 cells. Here we used animals with targeted deletion of the T-bet gene to determine its role in the progression of EAE. T...

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Bibliografiske detaljer
Main Authors: Nath, Narender, Prasad, Ratna, Giri, Shailendra, Singh, Avtar K, Singh, Inderjit
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2006
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782298/
https://ncbi.nlm.nih.gov/pubmed/16827899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02385.x
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