Cytotoxic T lymphocyte antigen-4-dependent down-modulation of costimulatory molecules on dendritic cells in CD4(+) CD25(+) regulatory T-cell-mediated suppression

We have previously demonstrated that CD4(+) CD25(+) natural regulatory T cells (Treg cells) induce down-modulation of CD80 and CD86 (B7) molecules on dendritic cells (DCs) in vitro. In this report we show that the extent of down-modulation is functionally significant because Treg-cell conditioned DC...

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Detalhes bibliográficos
Main Authors: Oderup, Cecilia, Cederbom, Lukas, Makowska, Anna, Cilio, Corrado M, Ivars, Fredrik
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782280/
https://ncbi.nlm.nih.gov/pubmed/16771859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02362.x
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