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Cd4(+)Cd25(+) Immune Regulatory Cells Are Required for Induction of Tolerance to Alloantigen via Costimulatory Blockade

Immune regulatory CD4(+)CD25(+) cells play a vital role in the induction and maintenance of self-tolerance and are essential for T cell homeostasis and the prevention of autoimmunity. Induction of tolerance to allogeneic donor grafts is a clinically desirable goal in bone marrow and solid organ tran...

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Autores principales: Taylor, Patricia A., Noelle, Randolph J., Blazar, Bruce R.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193378/
https://ncbi.nlm.nih.gov/pubmed/11390438
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