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HSP70 Enhances Immunosuppressive Function of CD4(+)CD25(+)FoxP3(+) T Regulatory Cells and Cytotoxicity in CD4(+)CD25(−) T Cells

Human CD4(+)CD25(+)FoxP3(+) T regulatory cells (Tregs) control effector T cells and play a central role in peripheral tolerance and immune homeostasis. Heat shock protein 70 (HSP70) is a major immunomodulatory molecule, but its effect on the functions of Tregs is not well understood. To investigate...

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書誌詳細
主要な著者: Wachstein, Julian, Tischer, Sabine, Figueiredo, Constanca, Limbourg, Anne, Falk, Christine, Immenschuh, Stephan, Blasczyk, Rainer, Eiz-Vesper, Britta
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530531/
https://ncbi.nlm.nih.gov/pubmed/23300563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051747
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