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Age-related loss of naïve T cells and dysregulation of T-cell/B-cell interactions in human lymph nodes

In this study we analysed the effects of age on T and B lymphocytes in human lymph nodes by comparing lymphocyte subsets in paraffin sections from lymph node tissue taken from healthy young and elderly people. We demonstrate that the relative number of CD8(+) T cells decreases with age but that the...

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Detalhes bibliográficos
Main Authors: Lazuardi, Lutfan, Jenewein, Brigitte, Wolf, Anna Maria, Pfister, Gerald, Tzankov, Alexandar, Grubeck-Loebenstein, Beatrix
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782064/
https://ncbi.nlm.nih.gov/pubmed/15606793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.02006.x
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