Long-Term Cytomegalovirus Infection Leads to Significant Changes in the Composition of the CD8(+) T-Cell Repertoire, Which May Be the Basis for an Imbalance in the Cytokine Production Profile in Elderly Persons

In spite of the present belief that latent cytomegalovirus (CMV) infection drives CD8(+) T-cell differentiation and induces premature immune senescence, no systematic studies have so far been performed to compare phenotypical and functional changes in the CD8(+) T-cell repertoire in CMV-infected and...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Almanzar, Giovanni, Schwaiger, Susanne, Jenewein, Brigitte, Keller, Michael, Herndler-Brandstetter, Dietmar, Würzner, Reinhard, Schönitzer, Diether, Grubeck-Loebenstein, Beatrix
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology 2005
الموضوعات:
Pathogenesis and Immunity
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC1075718/
https://ncbi.nlm.nih.gov/pubmed/15731261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.6.3675-3683.2005
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