Age-related appearance of a CMV-specific high-avidity CD8(+ )T cell clonotype which does not occur in young adults

Old age is associated with characteristic changes of the immune system contributing to higher incidence and severity of many infectious diseases. Particularly within the T cell compartment latent infection with human Cytomegalovirus (CMV) is contributing to and accelerating immunosenescence. However...

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Bibliografiske detaljer
Main Authors: Schwanninger, Angelika, Weinberger, Birgit, Weiskopf, Daniela, Herndler-Brandstetter, Dietmar, Reitinger, Stephan, Gassner, Christoph, Schennach, Harald, Parson, Walther, Würzner, Reinhard, Grubeck-Loebenstein, Beatrix
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Short Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596076/
https://ncbi.nlm.nih.gov/pubmed/19014475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4933-5-14
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