Age-related appearance of a CMV-specific high-avidity CD8(+ )T cell clonotype which does not occur in young adults

Old age is associated with characteristic changes of the immune system contributing to higher incidence and severity of many infectious diseases. Particularly within the T cell compartment latent infection with human Cytomegalovirus (CMV) is contributing to and accelerating immunosenescence. However...

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Detalhes bibliográficos
Main Authors: Schwanninger, Angelika, Weinberger, Birgit, Weiskopf, Daniela, Herndler-Brandstetter, Dietmar, Reitinger, Stephan, Gassner, Christoph, Schennach, Harald, Parson, Walther, Würzner, Reinhard, Grubeck-Loebenstein, Beatrix
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596076/
https://ncbi.nlm.nih.gov/pubmed/19014475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4933-5-14
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