The immunoregulatory effects of CMV-infection in human fibroblasts and the impact on cellular senescence

BACKGROUND: As a chronic antigenic stressor human Cytomegalovirus (CMV) contributes substantially to age-related alterations of the immune system. Even though monocytes have the greatest propensity for CMV-infection and seem to be an important host for the virus during latency, fibroblasts are also...

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Bibliographic Details
Main Authors: Wolf, Juliane, Weinberger, Birgit, Grubeck-Loebenstein, Beatrix
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Short Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364840/
https://ncbi.nlm.nih.gov/pubmed/22455503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4933-9-1
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