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Age-related appearance of a CMV-specific high-avidity CD8(+ )T cell clonotype which does not occur in young adults

Old age is associated with characteristic changes of the immune system contributing to higher incidence and severity of many infectious diseases. Particularly within the T cell compartment latent infection with human Cytomegalovirus (CMV) is contributing to and accelerating immunosenescence. However...

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Bibliografiska uppgifter
Huvudupphovsmän: Schwanninger, Angelika, Weinberger, Birgit, Weiskopf, Daniela, Herndler-Brandstetter, Dietmar, Reitinger, Stephan, Gassner, Christoph, Schennach, Harald, Parson, Walther, Würzner, Reinhard, Grubeck-Loebenstein, Beatrix
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596076/
https://ncbi.nlm.nih.gov/pubmed/19014475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4933-5-14
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