Effect of S5P α-helix charge mutants on inactivation of hERG K(+) channels

The ether-à-go-go (EAG) family of voltage-gated K(+) channels contains three subfamilies, EAG, ether-à-go-go related (ERG) and ether-à-go-go like (ELK). The human ether-à-go-go related gene (hERG) K(+) channel has been of significant interest because loss of function in the hERG channel is associate...

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Detalhes bibliográficos
Main Authors: Clarke, C E, Hill, A P, Zhao, J, Kondo, M, Subbiah, R N, Campbell, T J, Vandenberg, J I
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Molecular and Genomic
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779719/
https://ncbi.nlm.nih.gov/pubmed/16556651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.108332
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