KCNQ channels mediate I(Ks), a slow K(+) current regulating excitability in the rat node of Ranvier

Mutations that reduce the function of KCNQ2 channels cause neuronal hyperexcitability, manifested as epileptic seizures and myokymia. These channels are present in nodes of Ranvier in rat brain and nerve and have been proposed to mediate the slow nodal potassium current I(Ks). We have used immunocyt...

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Detalhes bibliográficos
Main Authors: Schwarz, J R, Glassmeier, G, Cooper, E C, Kao, T-C, Nodera, H, Tabuena, D, Kaji, R, Bostock, H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Cellular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779690/
https://ncbi.nlm.nih.gov/pubmed/16527853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.106815
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