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Made for “anchorin’”: Kv7.2/7.3 (KCNQ2/KCNQ3) channels and the modulation of neuronal excitability in vertebrate axons

Kv7.2 and Kv7.3 (encoded by KCNQ2 and KCNQ3) are homologous subunits forming a widely expressed neuronal voltage-gated K(+) (Kv) channel. Hypomorphic mutations in either KCNQ2 or KCNQ3 cause a highly penetrant, though transient, human phenotype--epilepsy during the first months of life. Some KCNQ2 m...

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Autor principal: Cooper, Edward C.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070838/
https://ncbi.nlm.nih.gov/pubmed/20940059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2010.10.001
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