Tamoxifen Inhibition of Kv7.2/Kv7.3 Channels

KCNQ genes encode five Kv7 K(+) channel subunits (Kv7.1–Kv7.5). Four of these (Kv7.2–Kv7.5) are expressed in the nervous system. Kv7.2 and Kv7.3 are the principal molecular components of the slow voltage-gated M-channel, which regulates neuronal excitability. In this study, we demonstrate that tamox...

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Detalhes bibliográficos
Main Authors: Ferrer, Tania, Aréchiga-Figueroa, Ivan Arael, Shapiro, Mark S., Tristani-Firouzi, Martin, Sanchez-Chapula, José A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782443/
https://ncbi.nlm.nih.gov/pubmed/24086693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076085
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