Differential Regulation of PI(4,5)P(2) Sensitivity of Kv7.2 and Kv7.3 Channels by Calmodulin

HIGHLIGHTS: - Calmodulin-dependent Kv7.2 current density without the need of binding calcium. - Kv7.2 current density increase is accompanied with resistance to PI(4,5)P(2) depletion. - Kv7.3 current density is insensitive to calmodulin elevation. - Kv7.3 is more sensitive to PI(4,5)P(2) depletion i...

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Gepubliceerd in:Front Mol Neurosci
Hoofdauteurs: Gomis-Perez, Carolina, Soldovieri, Maria V., Malo, Covadonga, Ambrosino, Paolo, Taglialatela, Maurizio, Areso, Pilar, Villarroel, Alvaro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2017
Onderwerpen:
Neuroscience
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410570/
https://ncbi.nlm.nih.gov/pubmed/28507506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00117
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