Pivoting between Calmodulin Lobes Triggered by Calcium in the Kv7.2/Calmodulin Complex

Kv7.2 (KCNQ2) is the principal molecular component of the slow voltage gated M-channel, which strongly influences neuronal excitability. Calmodulin (CaM) binds to two intracellular C-terminal segments of Kv7.2 channels, helices A and B, and it is required for exit from the endoplasmic reticulum. How...

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Bibliografiske detaljer
Main Authors: Alaimo, Alessandro, Alberdi, Araitz, Gomis-Perez, Carolina, Fernández-Orth, Juncal, Bernardo-Seisdedos, Ganeko, Malo, Covadonga, Millet, Oscar, Areso, Pilar, Villarroel, Alvaro
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904923/
https://ncbi.nlm.nih.gov/pubmed/24489773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086711
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