The Kv7.2/Kv7.3 Heterotetramer Assembles with a Random Subunit Arrangement

Voltage-gated K(+) channels composed of Kv7.2 and Kv7.3 are the predominant contributors to the M-current, which plays a key role in controlling neuronal activity. Various lines of evidence have indicated that Kv7.2 and Kv7.3 form a heteromeric channel. However, the subunit stoichiometry and arrange...

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Detalhes bibliográficos
Main Authors: Stewart, Andrew P., Gómez-Posada, Juan Camilo, McGeorge, Jessica, Rouhani, Maral J., Villarroel, Alvaro, Murrell-Lagnado, Ruth D., Edwardson, J. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320935/
https://ncbi.nlm.nih.gov/pubmed/22334706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.336511
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