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Influence of metabolic network structure and function on enzyme evolution

BACKGROUND: Most studies of molecular evolution are focused on individual genes and proteins. However, understanding the design principles and evolutionary properties of molecular networks requires a system-wide perspective. In the present work we connect molecular evolution on the gene level with s...

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Autors principals: Vitkup, Dennis, Kharchenko, Peter, Wagner, Andreas
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779518/
https://ncbi.nlm.nih.gov/pubmed/16684370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2006-7-5-r39
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