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Global probabilistic annotation of metabolic networks enables enzyme discovery

Annotation of organism-specific metabolic networks is one of the main challenges of systems biology. Importantly, due to inherent uncertainty of computational annotations, predictions of biochemical function need to be treated probabilistically. We present a global probabilistic approach to annotate...

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Main Authors: Plata, Germán, Fuhrer, Tobias, Hsiao, Tzu-Lin, Sauer, Uwe, Vitkup, Dennis
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696893/
https://ncbi.nlm.nih.gov/pubmed/22960854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1063
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