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Global probabilistic annotation of metabolic networks enables enzyme discovery

Annotation of organism-specific metabolic networks is one of the main challenges of systems biology. Importantly, due to inherent uncertainty of computational annotations, predictions of biochemical function need to be treated probabilistically. We present a global probabilistic approach to annotate...

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Bibliografiske detaljer
Main Authors: Plata, Germán, Fuhrer, Tobias, Hsiao, Tzu-Lin, Sauer, Uwe, Vitkup, Dennis
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696893/
https://ncbi.nlm.nih.gov/pubmed/22960854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1063
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