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Global probabilistic annotation of metabolic networks enables enzyme discovery

Annotation of organism-specific metabolic networks is one of the main challenges of systems biology. Importantly, due to inherent uncertainty of computational annotations, predictions of biochemical function need to be treated probabilistically. We present a global probabilistic approach to annotate...

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Bibliografske podrobnosti
Main Authors: Plata, Germán, Fuhrer, Tobias, Hsiao, Tzu-Lin, Sauer, Uwe, Vitkup, Dennis
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696893/
https://ncbi.nlm.nih.gov/pubmed/22960854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1063
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