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Influence of metabolic network structure and function on enzyme evolution

BACKGROUND: Most studies of molecular evolution are focused on individual genes and proteins. However, understanding the design principles and evolutionary properties of molecular networks requires a system-wide perspective. In the present work we connect molecular evolution on the gene level with s...

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Bibliographic Details
Main Authors: Vitkup, Dennis, Kharchenko, Peter, Wagner, Andreas
Format: Artigo
Language:Inglês
Published: BioMed Central 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779518/
https://ncbi.nlm.nih.gov/pubmed/16684370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2006-7-5-r39
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