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Identifying metabolic enzymes with multiple types of association evidence

BACKGROUND: Existing large-scale metabolic models of sequenced organisms commonly include enzymatic functions which can not be attributed to any gene in that organism. Existing computational strategies for identifying such missing genes rely primarily on sequence homology to known enzyme-encoding ge...

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Detalhes bibliográficos
Main Authors: Kharchenko, Peter, Chen, Lifeng, Freund, Yoav, Vitkup, Dennis, Church, George M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450304/
https://ncbi.nlm.nih.gov/pubmed/16571130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-177
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