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Investigation of the putative immunodominant T cell epitopes in coeliac disease
Background: Coeliac disease (CD) is an enteropathy mediated by gluten specific T cells which secrete interferon γ (IFN-γ) when stimulated by gluten peptides presented by HLA-DQ2 or DQ8 molecules. Residues 62–75 of α(2) gliadin have been proposed as the immunodominant epitope in the majority of CD pa...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Copyright 2003 by Gut
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1774960/ https://ncbi.nlm.nih.gov/pubmed/12524402 |
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