Investigation of the putative immunodominant T cell epitopes in coeliac disease

Background: Coeliac disease (CD) is an enteropathy mediated by gluten specific T cells which secrete interferon γ (IFN-γ) when stimulated by gluten peptides presented by HLA-DQ2 or DQ8 molecules. Residues 62–75 of α(2) gliadin have been proposed as the immunodominant epitope in the majority of CD pa...

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Autors principals: Ellis, H J, Pollock, E L, Engel, W, Fraser, J S, Rosen-Bronson, S, Wieser, H, Ciclitira, P J
Format: Artigo
Idioma:Inglês
Publicat: Copyright 2003 by Gut 2003
Matèries:
Coeliac Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774960/
https://ncbi.nlm.nih.gov/pubmed/12524402
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