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Antagonists and non‐toxic variants of the dominant wheat gliadin T cell epitope in coeliac disease
BACKGROUND: Coeliac disease (CD) is due to an inappropriate T cell mediated response to specific gluten peptides. Measured by interferon γ (IFN‐γ) ELISPOT, about half of the gliadin specific T cells induced with in vivo wheat gluten exposure in HLA‐DQ2+ CD are specific for an α/β‐gliadin peptide (p5...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMJ Group
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1856168/ https://ncbi.nlm.nih.gov/pubmed/16299041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.064550 |
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