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Cross linking to tissue transglutaminase and collagen favours gliadin toxicity in coeliac disease
BACKGROUND AND AIMS: Intestinal inflammation in coeliac disease is driven by the gluten fraction of wheat proteins. Deamidation or cross linking of gluten peptides by tissue transglutaminase (tTG), the coeliac disease autoantigen, creates potent T cell stimulatory peptides. Therefore, our aim was to...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMJ Group
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1856150/ https://ncbi.nlm.nih.gov/pubmed/16188922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.069385 |
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