Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn’s disease

Background: Nucleotide binding oligomerisation domain 2 (NOD2; also known as CARD15) mutations are associated with Crohn’s disease but how mutations cause disease is poorly understood. Innate immune responses are reportedly enhanced by combined NOD2 ligand (muramyl dipeptide, MDP) and Toll-like rece...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: van Heel, D A, Ghosh, S, Hunt, K A, Mathew, C G, Forbes, A, Jewell, D P, Playford, R J
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Copyright 2005 by Gut 2005
विषय:
Inflammatory Bowel Disease
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774767/
https://ncbi.nlm.nih.gov/pubmed/15928043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.065888
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