TGFβ induces morphological and molecular changes similar to human anterior subcapsular cataract

Background: Transforming growth factor β (TGFβ) has been shown to induce subcapsular plaques in cultured rat lenses as well as in lenses of transgenic mice. In the present study the authors have extended their analysis of these cataract models to determine how closely they mimic human cataract. In p...

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Autori principali: Lovicu, Frank J, Schulz, Mark W, Hales, Angela M, Vincent, Lisa N, Overbeek, Paul A, Chamberlain, Coral G, McAvoy, John W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright 2002 British Journal of Ophthalmology 2002
Soggetti:
Clinical Science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1771017/
https://ncbi.nlm.nih.gov/pubmed/11815351
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