Matrix Metalloproteinase-9–Null Mice Are Resistant to TGF-β–Induced Anterior Subcapsular Cataract Formation

Epithelial-mesenchymal transition (EMT) is associated with fibrotic diseases in the lens, such as anterior subcapsular cataract (ASC) formation. Often mediated by transforming growth factor (TGF)-β, EMT in the lens involves the transformation of lens epithelial cells into a multilayering of myofibro...

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Detalhes bibliográficos
Main Authors: Korol, Anna, Pino, Giuseppe, Dwivedi, Dhruva, Robertson, Jennifer V., Deschamps, Paula A., West-Mays, Judith A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076463/
https://ncbi.nlm.nih.gov/pubmed/24814605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.03.013
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