Adenoviral gene transfer of bioactive TGFβ1 to the rodent eye as a novel model for anterior subcapsular cataract

PURPOSE: To produce a gene-transfer model of rodent anterior subcapsular cataracts (ASC) using a replication-deficient, adenoviral vector containing active TGFβ1. Establishment of this model will be important for further investigations of TGFβ-induced signaling cascades in ASC. METHODS: Adenovirus c...

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Main Authors: Robertson, Jennifer V., Nathu, Zahra, Najjar, Anas, Dwivedi, Dhruva, Gauldie, Jack, West-Mays, Judith A.
Format: Artigo
Jezik:Inglês
Izdano: Molecular Vision 2007
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647562/
https://ncbi.nlm.nih.gov/pubmed/17417606
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