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Matrix Metalloproteinase Inhibitors Suppress Transforming Growth Factor-β-Induced Subcapsular Cataract Formation

The pleotropic morphogen transforming growth factor-β (TGFβ) plays an important role in the development of fibrotic pathologies, including anterior subcapsular cataracts (ASCs). ASC formation involves increased proliferation and transition of lens epithelial cells into myofibroblasts, through epithe...

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Detalhes bibliográficos
Main Authors: Dwivedi, Dhruva J., Pino, Giuseppe, Banh, Alice, Nathu, Zahra, Howchin, Derek, Margetts, Peter, Sivak, Jacob G., West-Mays, Judith A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592675/
https://ncbi.nlm.nih.gov/pubmed/16400010
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