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TGFβ promotes Wnt expression during cataract development

TGFβ induces lens epithelial cells to undergo epithelial mesenchymal transition (EMT) and many changes with characteristics of fibrosis including posterior capsular opacification (PCO). Consequently much effort is directed at trying to block the damaging effects of TGFβ in the lens. To do this effec...

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Hlavní autoři: Chong, CCW, Stump, RJW, Lovicu, FJ, McAvoy, JW
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683259/
https://ncbi.nlm.nih.gov/pubmed/18789926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2008.07.018
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