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TGFβ promotes Wnt expression during cataract development

TGFβ induces lens epithelial cells to undergo epithelial mesenchymal transition (EMT) and many changes with characteristics of fibrosis including posterior capsular opacification (PCO). Consequently much effort is directed at trying to block the damaging effects of TGFβ in the lens. To do this effec...

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Dettagli Bibliografici
Autori principali: Chong, CCW, Stump, RJW, Lovicu, FJ, McAvoy, JW
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683259/
https://ncbi.nlm.nih.gov/pubmed/18789926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2008.07.018
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