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Phenobarbital Regulates Nuclear Expression of HNF-4α in Mouse and Rat Hepatocytes Independent of CAR and PXR
Phenobarbital is a lipophilic molecule used as a sedative and antiepileptic drug that elicits a multitude of effects in the liver, including gross liver enlargement, hepatocyte hypertrophy, and induced expression of drug-metabolizing enzymes and other liver-specific genes. The constitutive androstan...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1769339/ https://ncbi.nlm.nih.gov/pubmed/16799975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.21234 |
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