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Substrate Recognition, Protein Dynamics, and Iron-Sulfur Cluster in Pseudomonas aeruginosa Adenosine 5′-Phosphosulfate Reductase
APS reductase catalyzes the first committed step of reductive sulfate assimilation in pathogenic bacteria, including Mycobacterium tuberculosis, and is a promising target for drug development. We report the 2.7 Å resolution crystal structure of Pseudomonas aeruginosa APS reductase in the thiosulfona...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1769331/ https://ncbi.nlm.nih.gov/pubmed/17010373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.08 |
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