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Identification of Critical Ligand Binding Determinants in Mycobacterium tuberculosis Adenosine-5′-Phosphosulfate Reductase

Mycobacterium tuberculosis adenosine 5′-phosphosulfate (APS) reductase is an iron-sulfur protein and a validated target to develop new anti-tubercular agents, particularly for the treatment of latent infection. To facilitate the development of potent and specific inhibitors of APS reductase, we have...

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Main Authors: Hong, Jiyoung A., Bhave, Devayani P., Carroll, Kate S.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749248/
https://ncbi.nlm.nih.gov/pubmed/19678707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm900728u
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