Substrate Recognition, Protein Dynamics, and Iron-Sulfur Cluster in Pseudomonas aeruginosa Adenosine 5′-Phosphosulfate Reductase

APS reductase catalyzes the first committed step of reductive sulfate assimilation in pathogenic bacteria, including Mycobacterium tuberculosis, and is a promising target for drug development. We report the 2.7 Å resolution crystal structure of Pseudomonas aeruginosa APS reductase in the thiosulfona...

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Hauptverfasser: Chartron, Justin, Carroll, Kate S., Shiau, Carrie, Gao, Hong, Leary, Julie A., Bertozzi, Carolyn R., Stout, C. David
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1769331/
https://ncbi.nlm.nih.gov/pubmed/17010373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.08
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