SST3-selective potent peptidic somatostatin receptor antagonists

A family of octapeptide derivatives of somatostatin cyclized via a disulfide bridge (des-AA(1,2,4,5,12,13)[d-2Nal(8)]-somatostatin-14, ODN-8) was identified that has high affinity and selectivity for the human sst(3) somatostatin receptor subtype transfected in CCL39 cells. The binding affinity of c...

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Hlavní autoři: Reubi, Jean Claude, Schaer, Jean-Claude, Wenger, Sandra, Hoeger, Carl, Erchegyi, Judit, Waser, Beatrice, Rivier, Jean
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2000
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC17685/
https://ncbi.nlm.nih.gov/pubmed/11095748
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