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Direct observation in solution of a preexisting structural equilibrium for a mutant of the allosteric aspartate transcarbamoylase

Many signaling and metabolic pathways rely on the ability of some of the proteins involved to undergo a substrate-induced transition between at least two structural states. Among the various models put forward to account for binding and activity curves of those allosteric proteins, the Monod, Wyman,...

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Detalhes bibliográficos
Main Authors: Fetler, Luc, Kantrowitz, Evan R., Vachette, Patrice
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1766413/
https://ncbi.nlm.nih.gov/pubmed/17202260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607641104
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