Mutations in the connection domain of HIV-1 reverse transcriptase increase 3′-azido-3′-deoxythymidine resistance

We previously proposed that a balance between nucleotide excision and template RNA degradation plays an important role in nucleoside reverse transcriptase inhibitor (NRTI) resistance. To explore the predictions of this concept, we analyzed the role of patient-derived C-terminal domains of HIV-1 reve...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Nikolenko, Galina N., Delviks-Frankenberry, Krista A., Palmer, Sarah, Maldarelli, Frank, Fivash, Matthew J., Coffin, John M., Pathak, Vinay K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1765458/
https://ncbi.nlm.nih.gov/pubmed/17179211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609642104
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados