Par4 is required for platelet thrombus propagation but not fibrin generation in a mouse model of thrombosis

Thrombin, a central mediator of hemostasis and thrombosis, converts fibrinogen to fibrin and is a potent platelet activator. Activated platelets provide a surface for assembly of the tenase and prothrombinase complexes required for thrombin generation. The role of thrombin-induced platelet activatio...

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Detaylı Bibliyografya
Asıl Yazarlar: Vandendries, Erik R., Hamilton, Justin R., Coughlin, Shaun R., Furie, Bruce, Furie, Barbara C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2007
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1765451/
https://ncbi.nlm.nih.gov/pubmed/17190826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610188104
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