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Distinguishing between cooperative and unimodal downhill protein folding

Conventional cooperative protein folding invokes discrete ensembles of native and denatured state structures in separate free-energy wells. Unimodal noncooperative (“downhill”) folding, however, proposes an ensemble of states occupying a single free-energy well for proteins folding at ≥4 × 10(4) s(−...

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Detalhes bibliográficos
Main Authors: Huang, Fang, Sato, Satoshi, Sharpe, Timothy D., Ying, Liming, Fersht, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1765421/
https://ncbi.nlm.nih.gov/pubmed/17200301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609717104
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