Directed biosynthesis of new saframycin derivatives with resting cells of Streptomyces lavendulae.

Saframycin A is an antitumor antibiotic produced by Streptomyces lavendulae 314 which falls into the category of the N-heterocyclic quinone group. Biosynthetically the quinone ring is derived from two tyrosine molecules which condense to generate the basic ring system of saframycin A. The side chain...

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Bibliographic Details
Main Authors: Arai, T, Yazawa, K, Takahashi, K, Maeda, A, Mikami, Y
Format: Artigo
Language:Inglês
Published: 1985
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC176299/
https://ncbi.nlm.nih.gov/pubmed/3839995
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